The Children’s Tumor Foundation is a non-profit 501(c)(3) medical foundation,dedicated to finding effective treatments for the millions of people worldwide living with neurofibromatosis (NF), a term for three distinct disorders: NF1, NF2, and schwannomatosis. NF causes tumors to grow on nerves throughout the body and can lead to blindness, bone abnormalities, cancer, deafness, disfigurement, learning disabilities, and excruciating and disabling pain.

NF affects one in every 3,000 people, equally across all populations. The Children’s Tumor Foundation collaborates and funds critical research into neurofibromatosis that will lead to more effective and safe treatments for those who suffer from NF. In addition to benefiting those who live with NF, this research is shedding new light on several forms of cancer, brain tumors, bone abnormalities, and learning disabilities, ultimately benefiting the broader community.

JOB TITLE: Basic Science Manager

DEPARTMENT: Research and Development

REPORTS TO: Vice President, Research and Development

SCOPE OF RESPONSIBILITIES: The Basic Science Manager will work as part of a team of multidisciplinary PhD scientists, and will interact with a consortium of leading scientific and medical clinicians in a collaborative approach with the goal of speeding up the NF drug discovery process. The focus of the Manager will be to supervise and coordinate all the basic science activities across various projects and maximize their results by creating new synergies. They will develop and manage the repository platform for NF data across a variety of ongoing projects, and will collaborate with Sage Bionetworks for the integration of data into the Synapse portal. The Basic Science Manager will use bioinformatics tools available at CTF to help researchers with data interpretation and analysis. Additionally, the Basic Science Manager will manage the Young Investigator Awards (YIA) grant review and award process, and collaborate with the Communications department to creatively communicate breakthrough findings in newsletters and marketing materials.

PRIMARY ACCOUNTABILITIES:

Supervise and implement the expansion of the repository platform for NF data to accommodate external data from other projects.

Engage the research community in the use of the repository platform for NF data.

Assist NF researchers in the use of the data analysis tools that the Children’s Tumor Foundation has available.

Ensure that all data from various projects are regularly stored in Sage and available to the broader community.

Seek to expand the panel of YIA reviewers to include new subject matter experts.

Integrate YIA research data in the CTF-managed database hosted by Sage Bionetworks, as well as the Microedge GIFT platform.

Monitor scientific literature, report to the communications department regarding major scientific findings and assist in writing highlights for newsletters and blogs.

Liaise with the Science Consortia to set milestones and deliverables, anticipate and manage changes to projects, and support the consortium groups with development, plans and reporting.

REQUIREMENTS:

PhD in biology, bioinformatics, biochemistry, molecular biology, pharmacology or related field is required.

5+ years hands-on experience in biology, bioinformatics, biochemistry, molecular biology, pharmacology or related field is required.

3 years of experience in data management and big data analysis is required.

At least 3 years of postdoctoral experience in NF research is preferred.

Knowledge of the Microedge GIFT platform and experience in writing and reviewing scientific literature and grants is preferred.

Knowledge of Thomson Reuters ‘Metacore,’ ‘Metaminer’ and/or other bioinformatic tools is preferred.

Project management skills as well as the ability to use project management tools (Gantt charts) is preferred.

How to apply

Applications must include a resume, cover letter, and salary history and/or requirements, and can be submitted via email to cblessing@ctf.org,